Bestsel

BeStSel (Beta Structure Selection) is a novel method for the secondary structure determination and fold recognition from protein circular dichroism spectra.

		Single spectrum analysis and fold recognition
		Secondary structure determination distinguishing parallel beta-sheets and antiparallel beta-sheets of different twists, and fold recognition from the CD spectrum.

Fold recognition
Prediction of fold class, architecture, topology and homology for the provided secondary structure contents.

		Multiple spectra analysis
		Analysis of a series of spectra as a function of temperature, time, ligand concentration, etc.

Secondary structure and beta-sheet decomposition for PDB structures
Secondary structure composition of protein structures deposited in PDB on the basis of the eight structural element decomposed by BeStSel. For comparison, DSSP data and Selcon3 decomposition is also calculated.

This is a test verson of BeStSel. Here we provide basic information on the algorithm and its use. Detailed information is available in Micsonai et al., Proc. Natl. Acad. Sci. USA (2015) doi:10.1073/pnas.1500851112.

What are the secondary structure basis components of BeStSel?

How the fitting to the CD spectrum is carried out in BeStSel?

Considerations for wavelength range selection and the importance of the correct protein concentration

How are the closest structures found in the entire PDB?

How are the closest single CATH domains found in the filtered PDB subset?

How are the structural domains found within the expected error of BeStSel?

On the analysis of peptide CD by BeStSel

Bugfixes